Quarterly report pursuant to Section 13 or 15(d)

Supplemental Disclosure of Non-cash Activity (Details)

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Supplemental Disclosure of Non-cash Activity (Details) - USD ($)
 3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Income taxes $ 0 $ 0  
Cash paid for interest 11,250 35,533  
Net deferred revenue 18,540,992   $ 18,650,813
Stock option proceeds receivable 11,201 49,360  
License Fee Collection Upon Regional Developer Agreement      
Net deferred revenue 95,197 $ 35,679  
Purchase of Property, Plant and Equipment Included in Accounts Payable      
Capital expenditures incurred but not yet paid $ 109,882   158,293
Purchase of Property, Plant and Equipment Included in Accrued Expenses      
Capital expenditures incurred but not yet paid     $ 152,501